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Phosphotungstic Acid Preventing Urinary Calculi

Phosphotungstic acid preventing urinary calculi is a tungsten compound containing phosphotungstic acid as allopurinol alternatives, to prevent urolithiasis. +6 valance state of tungstate can oxidize uric acid in the human body to generate urea, it can easily dissolve in water and eliminate from body, at the same time will reduce side effects of uric acid caused to human body, also guarantees xanthine oxidase, aldehyde oxidase, sulfite oxidase normal biochemical metabolic processes in the human body are not affected. Tungstate is also soluble in water and can be eliminated easily which accumulation and side effects to human body.

phosphotungstic acid solid imagekidney stones SEM

At present, we haven’t found related enzyme related to tungsten, but it supplies tungsten and molybdenum at the same time which helps the body metabolism of excess uric acid. Uric acid reacting with tungsten to generate urea with phosphoric, it is the most important reaction of tungstic and tungstate in human body, the process is:
Uric acid+ Phosphoric acid = CO2 + Tungsten blue

Urolithiasis means urine concentrates into particles or massive aggregates includes kidney stones, ureteral stones, bladder stones and urinary tract stones, frequently happens on young adults, the incidents shows an upward trend in recent years.

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